Slough Secondary School was the first major co-educational selective school established in Slough (originally Buckinghamshire, now Berkshire), and occupied a building in William Street in the Town Centre. The William Street building was replaced by the tower block which is now the Slough Campus of Thames Valley University.
Headteachers
- 1912 – 1925 Mr W Francis-Smith
- 1923 – 1925 Mr B Llewellyn (Acting)
- 1925 – 1936 Mr E Rudland Clarke (continued as head of Slough Grammar School for Boys until 1952)